Wednesday, October 12, 2016

Crestor


Crestor is a brand name of rosuvastatin, approved by the FDA in the following formulation(s):


CRESTOR (rosuvastatin calcium - tablet; oral)



  • Manufacturer: IPR

    Approval date: August 12, 2003

    Strength(s): 10MG, 20MG, 40MG [RLD], 5MG

Has a generic version of Crestor been approved?


No. There is currently no therapeutically equivalent version of Crestor available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Crestor. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Pharmaceutical compositions
    Patent 6,316,460
    Issued: November 13, 2001
    Inventor(s): Creekmore; Joseph R & Wiggins; Norman A.
    Assignee(s): Astrazeneca AB
    The invention concerns a pharmaceutical composition comprising the HMG CoA reductase inhibitor (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrim idin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically acceptable salt thereof as the active ingredient, which remains stable over a prolonged period.
    Patent expiration dates:

    • August 4, 2020
      ✓ 
      Drug product


    • February 4, 2021
      ✓ 
      Pediatric exclusivity




  • Use of rosuvastatin (zd-4522) in the treatment of heterozygous familial hypercholesterolemia
    Patent 6,858,618
    Issued: February 22, 2005
    Inventor(s): Raza; Ali & Hutchinson; Howard Gerard
    Assignee(s): AstraZeneca AB
    The invention provides a method for the treatment of heterozygous familial hypercholesterolemia by administering the compound (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically acceptable salt thereof.
    Patent expiration dates:

    • December 17, 2021
      ✓ 
      Patent use: USE OF ROSUVASTATIN CALCIUM TO REDUCE ELEVATED TOTAL-C, LDL-C, APOB, NONHDL-C OR TG LEVELS; TO INCREASE HDL-C IN ADULT PATIENTS WITH PRIMARY HYPERLIPIDEMIA OR MIXED DYSLIPIDEMIA; AND TO SLOW THE PROGRESSION OF ATHEROSCLEROSIS.


    • June 17, 2022
      ✓ 
      Pediatric exclusivity




  • Systematic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases and as tools to aid in the selection of agents to be used for the prevention and treatment of atherosclerotic disease
    Patent 7,030,152
    Issued: April 18, 2006
    Inventor(s): Ridker; Paul & Hennekens; Charles H.
    Assignee(s): The Brigham and Women's Hospital, Inc.
    The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
    Patent expiration dates:

    • April 2, 2018
      ✓ 
      Patent use: USE OF ROSUVASTATIN CALCIUM FOR THE PRIMARY PREVENTION OF CARDIOVASCULAR DISEASE IN INDIVIDUALS WITHOUT CLINICALLY EVIDENT CORONARY HEART DISEASE BUT WITH INCREASED RISK FACTORS


    • October 2, 2018
      ✓ 
      Pediatric exclusivity




  • Systemic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases and as tools to aid in the selection of agents to be used for the prevention and treatment of atherosclerotic disease
    Patent 7,964,614
    Issued: June 21, 2011
    Inventor(s): Ridker; Paul & Hennekens; Charles H.
    Assignee(s): The Brigham and Women's Hospital, Inc.
    The invention involves methods for characterizing an individual's risk profile of developing a future cardiovascular disorder by obtaining a level of the marker of systemic inflammation in the individual. The invention also involves methods for evaluating the likelihood that an individual will benefit from treatment with an agent for reducing the risk of future cardiovascular disorder.
    Patent expiration dates:

    • April 2, 2018
      ✓ 
      Patent use: USE OF ROSUVASTATIN CALCIUM FOR THE PRIMARY PREVENTION OF CARDIOVASCULAR DISEASE IN INDIVIDUALS WITHOUT CLINICALLY EVIDENT CORONARY HEART DISEASE BUT WITH INCREASED RISK FACTORS


    • October 2, 2018
      ✓ 
      Pediatric exclusivity




  • Pyrimidine derivatives
    Patent RE37314
    Issued: August 7, 2001
    Inventor(s): Hirai; Kentaro & Ishiba; Teruyuki & Koike; Haruo & Watanabe; Masamichi
    Assignee(s): Shionogi Seiyaku Kabushiki Kaisha
    The compounds of the present invention inhibit the HMG-CoA reductase, and subsequently suppress the biosynthesis of cholesterol. And they are useful in the treatment of hypercholesterolemia, hyperlipoproteinemia, and atherosclerosis.
    Patent expiration dates:

    • January 8, 2016
      ✓ 
      Drug substance


    • July 8, 2016
      ✓ 
      Pediatric exclusivity



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • November 8, 2010 - ADJUNCTIVE THERAPY TO DIET TO SLOW THE PROGRESSION OF ARTHEROSCLEROSIS IN ADULT PATIENTS AS PART OF A TREATMENT STRATEGY TO LOWER TOTAL-C AND LDL-C TO TARGET LEVELS

    • May 8, 2011 - PEDIATRIC EXCLUSIVITY

    • November 6, 2011 - TO TREAT PATIENTS WITH PRIMARY DYSBETALIPOPROTEINEMIA (FREDICKSON TYPE III HYPERLIPOPROTEINEMIA) AS AN ADJUNCT TO DIET

    • May 6, 2012 - PEDIATRIC EXCLUSIVITY

    • October 16, 2012 - TREATMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA IN ADOLESCENT BOYS AND POSTMENARCHAL GIRLS, AGES 10 TO 17 YEARS, WITH A RECOMMENDATION DOSING RANGE OF 5 TO 20 MG ONCE DAILY

    • February 8, 2013 - PRIMARY PREVENTION OF CARDIOVASCULAR DISEASE, BASED ON THE RESULTS OF JUSTIFICATION FOR THE USE OF STATINS IN PRIMARY PREVENTION; AN INTERVENTION TRIAL EVALUATING ROSUVASTATIN (JUPITER)

    • April 16, 2013 - PEDIATRIC EXCLUSIVITY

See also...

  • Crestor Consumer Information (Drugs.com)
  • Crestor Consumer Information (Wolters Kluwer)
  • Crestor Consumer Information (Cerner Multum)
  • Crestor Advanced Consumer Information (Micromedex)
  • Crestor AHFS DI Monographs (ASHP)
  • Rosuvastatin Consumer Information (Wolters Kluwer)
  • Rosuvastatin Consumer Information (Cerner Multum)
  • Rosuvastatin Advanced Consumer Information (Micromedex)
  • Rosuvastatin Calcium AHFS DI Monographs (ASHP)

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